CELSR1 polyclonal antibody
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More Files
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Immunofluorescence
Immunofluorescence analysis of MCF-7 cells, using CELSR1 polyclonal antibody (Cat # PAB17503).
Peptide "+" means "with peptide blocking".
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CELSR1.
Immunogen
A synthetic peptide corresponding to amino acids 921-970 of human CELSR1.
Host
Rabbit
Theoretical MW (kDa)
329
Reactivity
Human, Mouse, Rat
Specificity
This antibody detects endogenous levels of total CELSR1 protein
Form
Liquid
Purification
Affinity chromatography
Recommend Usage
ELISA (1:10000)
Immunofluorescence (1:100-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (without Mg2+ and Ca2+), pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol).
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunofluorescence
Immunofluorescence analysis of MCF-7 cells, using CELSR1 polyclonal antibody (Cat # PAB17503).
Peptide "+" means "with peptide blocking".Enzyme-linked Immunoabsorbent Assay
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Gene Info — CELSR1
Entrez GeneID
9620Protein Accession#
Q9NYQ6Gene Name
CELSR1
Gene Alias
CDHF9, DKFZp434P0729, FMI2, HFMI2, ME2
Gene Description
cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
Omim ID
604523Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. This particular member is a developmentally regulated, neural-specific gene which plays an unspecified role in early embryogenesis. [provided by RefSeq
Other Designations
OTTHUMP00000028852|cadherin EGF LAG seven-pass G-type receptor 1|protocadherin flamingo 2
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Interactome
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Disease
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