MED13 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of MED13.
Immunogen
A synthetic peptide corresponding to internal of human MED13.
Host
Rabbit
Reactivity
Human
Specificity
This antibody detects endogenous levels of total MED13 protein.
Form
Liquid
Recommend Usage
Immunohistochemistry (1:50-1:100)
ELISA (1:40000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using MED13 polyclonal antibody (Cat # PAB17466).
Peptide "+" means "with peptide blocking".Enzyme-linked Immunoabsorbent Assay
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Gene Info — MED13
Entrez GeneID
9969Protein Accession#
Q9UHV7Gene Name
MED13
Gene Alias
ARC250, DRIP250, HSPC221, KIAA0593, THRAP1, TRAP240
Gene Description
mediator complex subunit 13
Omim ID
603808Gene Ontology
HyperlinkGene Summary
This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. The product of this gene is proposed to form a sub-complex with MED12, cyclin C, and CDK8 that can negatively regulate transactivation by mediator. [provided by RefSeq
Other Designations
activator-recruited cofactor 250 kDa component|mediator of RNA polymerase II transcription, subunit 13 homolog|thyroid hormone receptor associated protein 1|thyroid hormone receptor-associated protein complex component TRAP240|thyroid hormone receptor-ass
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Interactome
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