TRPS1 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using TRPS1 polyclonal antibody (Cat # PAB17465).
Peptide "+" means "with peptide blocking".
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TRPS1.
Immunogen
A synthetic peptide corresponding to amino acids 121-170 of human TRPS1.
Host
Rabbit
Reactivity
Human, Mouse
Specificity
This antibody detects endogenous levels of total TRPS1 protein.
Form
Liquid
Recommend Usage
Immunohistochemistry (1:50-1:100)
ELISA (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using TRPS1 polyclonal antibody (Cat # PAB17465).
Peptide "+" means "with peptide blocking".Enzyme-linked Immunoabsorbent Assay
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Gene Info — TRPS1
Entrez GeneID
7227Protein Accession#
Q9UHF7Gene Name
TRPS1
Gene Alias
GC79, LGCR, MGC134928
Gene Description
trichorhinophalangeal syndrome I
Gene Ontology
HyperlinkGene Summary
This gene encodes a transcription factor that represses GATA-regulated genes and binds to a dynein light chain protein. Binding of the encoded protein to the dynein light chain protein affects binding to GATA consensus sequences and suppresses its transcriptional activity. Defects in this gene are a cause of tricho-rhino-phalangeal syndrome (TRPS) types I-III. [provided by RefSeq
Other Designations
OTTHUMP00000183498|zinc finger transcription factor TRPS1
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Interactome
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Disease
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Publication Reference
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A novel TRPS1 mutation in a family with tricho-rhino-phalangeal syndrome type 1.
Fujisawa T, Fukao T, Shimomura Y, Seishima M.
The Journal of Dermatology 2014 Jun; 41(6):514.
Application：IHC, Human, Scalp skin.
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Transcriptional repression of the Dspp gene leads to dentinogenesis imperfecta phenotype in Col1a1-Trps1 transgenic mice.
Napierala D, Sun Y, Maciejewska I, Bertin TK, Dawson B, D'Souza R, Qin C, Lee B.
Journal of Bone and Mineral Research 2012 Aug; 27(8):1735.
Application：IHC-P, Mouse, Mouse heads.
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A novel TRPS1 mutation in a family with tricho-rhino-phalangeal syndrome type 1.
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