Western blot analysis of extracts from HepG2 cells (Lane 1), Jurkat cells (Lane 2) and HUVEC cells (Lane 3 and lane 4), using ERAP1 polyclonal antibody (Cat # PAB17464). Peptide "+" means "with peptide blocking".
Aminopeptidases play a role in the metabolism of several peptides that may be involved in blood pressure and the pathogenesis of essential hypertension (MIM 145500). Adipocyte-derived leucine aminopeptidase (ALAP) is a member of the M1 family of zinc metallopeptidases.[supplied by OMIM