DUS2L polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of extracts from Raw 264.7 cells, using DUS2L polyclonal antibody (Cat # PAB17461).
Peptide "+" means "with peptide blocking".
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry analysis of paraffin-embedded human skeletal muscle using DUS2L polyclonal antibody (Cat # PAB17461).
Peptide "+" means "with peptide blocking".
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of DUS2L.
Immunogen
A synthetic peptide corresponding to C-terminus of human DUS2L.
Host
Rabbit
Reactivity
Human, Mouse
Specificity
This antibody detects endogenous levels of total DUS2L protein.
Form
Liquid
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:100)
ELISA (1:20000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of extracts from Raw 264.7 cells, using DUS2L polyclonal antibody (Cat # PAB17461).
Peptide "+" means "with peptide blocking".Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry analysis of paraffin-embedded human skeletal muscle using DUS2L polyclonal antibody (Cat # PAB17461).
Peptide "+" means "with peptide blocking".Enzyme-linked Immunoabsorbent Assay
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Gene Info — DUS2L
Entrez GeneID
54920Protein Accession#
Q9NX74Gene Name
DUS2L
Gene Alias
DUS2, FLJ20399, SMM1, URLC8
Gene Description
dihydrouridine synthase 2-like, SMM1 homolog (S. cerevisiae)
Omim ID
609707Gene Ontology
HyperlinkGene Summary
Dihydrouridine synthase catalyzes reduction of the 5,6-double bond of a uridine residue on the displacement loop of tRNA. The resultant modified base, 5,6-dihydrouridine, appears to increase the conformational flexibility and dynamic motion of tRNA (Kato et al., 2005 [PubMed 15994936]).[supplied by OMIM
Other Designations
dihydrouridine synthase 2-like, SMM1 homolog|up-regulated in lung cancer 8
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