XRN2 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of XRN2.
Immunogen
A synthetic peptide corresponding to internal of human XRN2.
Host
Rabbit
Reactivity
Human, Mouse
Specificity
This antibody detects endogenous levels of total XRN2 protein.
Form
Liquid
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:100)
ELISA (1:5000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of extracts from COS-7 cells, using XRN2 polyclonal antibody (Cat # PAB17450).
Peptide "+" means "with peptide blocking".Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using XRN2 polyclonal antibody (Cat # PAB17450).
Peptide "+" means "with peptide blocking".Enzyme-linked Immunoabsorbent Assay
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Gene Info — XRN2
Entrez GeneID
22803Protein Accession#
Q9H0D6Gene Name
XRN2
Gene Alias
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Gene Description
5'-3' exoribonuclease 2
Omim ID
608851Gene Ontology
HyperlinkGene Summary
This gene shares similarity with the mouse Dhm1 and the yeast dhp1 gene. The yeast gene is involved in homologous recombination and RNA metabolism, such as RNA synthesis and RNA trafficking. Complementation studies show that Dhm1 has a similar function in mouse as dhp1. The function of the human gene has not yet been determined. Transcript variants encoding different isoforms have been noted for this gene; however, their full-length nature is not known. [provided by RefSeq
Other Designations
Dhm1-like protein (mouse homolog)|OTTHUMP00000030403
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