ATF6B polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of extracts from COLO 205 cells, using ATF6B polyclonal antibody (Cat # PAB17440).
Peptide "+" means "with peptide blocking".
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of ATF6B.
Immunogen
A synthetic peptide corresponding to internal of human ATF6B.
Host
Rabbit
Reactivity
Human
Specificity
This antibody detects endogenous levels of total ATF6B protein.
Form
Liquid
Recommend Usage
Western Blot (1:500-1:1000)
ELISA (1:20000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of extracts from COLO 205 cells, using ATF6B polyclonal antibody (Cat # PAB17440).
Peptide "+" means "with peptide blocking".Enzyme-linked Immunoabsorbent Assay
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Gene Info — ATF6B
Entrez GeneID
1388Protein Accession#
Q99941Gene Name
ATF6B
Gene Alias
CREB-RP, CREBL1, FLJ10066, G13
Gene Description
activating transcription factor 6 beta
Omim ID
600984Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
Creb-related protein|OTTHUMP00000029433|cAMP responsive element binding protein-like 1|cyclic AMP-dependent transcription factor ATF-6 beta|protein G13
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Interactome
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Disease
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