MKL1 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of extracts from HeLa cells (Lane 1) and HUVEC cells (Lane 2 and lane 3), using MKL1 polyclonal antibody (Cat # PAB17429).
Peptide "+" means "with peptide blocking".
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of MKL1.
Immunogen
A synthetic peptide corresponding to N-terminus of human MKL1.
Host
Rabbit
Reactivity
Human, Mouse
Specificity
This antibody detects endogenous levels of total MKL1 protein.
Form
Liquid
Recommend Usage
Western Blot (1:500-1:1000)
ELISA (1:10000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of extracts from HeLa cells (Lane 1) and HUVEC cells (Lane 2 and lane 3), using MKL1 polyclonal antibody (Cat # PAB17429).
Peptide "+" means "with peptide blocking".Enzyme-linked Immunoabsorbent Assay
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Gene Info — MKL1
Entrez GeneID
57591Protein Accession#
Q969V6Gene Name
MKL1
Gene Alias
BSAC, MAL, MRTF-A
Gene Description
megakaryoblastic leukemia (translocation) 1
Omim ID
606078Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. [provided by RefSeq
Other Designations
OTTHUMP00000028831|RBM15/MKL1 fusion|RNA-binding motif protein 15/megakaryoblastic leukemia-1 fusion protein|basic, SAP and coiled-coil domain|megakaryoblastic leukemia 1|megakaryoblastic leukemia 1 protein|megakaryocytic acute leukemia|myocardin-related
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Interactome
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Disease
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