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Last updated: 2017/3/19
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PSMD4 polyclonal antibody

  • Catalog # : PAB1741
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of PSMD4.
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human PSMD4.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein G purification
  • Recommend Usage:
  • Western Blot (1:1000)
    Immunohistochemistry (1:50-100)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • The PSMD4 polyclonal antibody (Cat # PAB1741) is used in Western blot to detect PSMD4 in Jurkat cell lysate.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Formalin-fixed and paraffin-embedded human cancer tissue reacted with PSMD4 polyclonal antibody (Cat # PAB1741) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma.
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 5710
  • Gene Name:
  • PSMD4
  • Gene Alias:
  • AF,AF-1,ASF,MCB1,Rpn10,S5A,pUB-R5
  • Gene Description:
  • proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
  • Gene Summary:
  • The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. Pseudogenes have been identified on chromosomes 10 and 21. [provided by RefSeq
  • Other Designations:
  • 26S protease subunit S5a,26S proteasome non-ATPase regulatory subunit 4,OTTHUMP00000014286,OTTHUMP00000059963,S5a/antisecretory factor protein,angiocidin,antisecretory factor 1,multiubiquitin chain binding protein,proteasome 26S non-ATPase subunit 4
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