UBXN11 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of extracts from HepG2 cells, using UBXN11 polyclonal antibody (Cat # PAB17394).
Peptide "+" means "with peptide blocking".
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using UBXN11 polyclonal antibody (Cat # PAB17394).
Peptide "+" means "with peptide blocking".
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of UBXN11.
Immunogen
A synthetic peptide corresponding to internal of human UBXN11.
Host
Rabbit
Reactivity
Human
Specificity
This antibody detects endogenous levels of total UBXN11 protein.
Form
Liquid
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:100)
ELISA (1:20000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of extracts from HepG2 cells, using UBXN11 polyclonal antibody (Cat # PAB17394).
Peptide "+" means "with peptide blocking".Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using UBXN11 polyclonal antibody (Cat # PAB17394).
Peptide "+" means "with peptide blocking". -
Gene Info — UBXN11
Entrez GeneID
91544Protein Accession#
Q5T124Gene Name
UBXN11
Gene Alias
COA-1, DKFZp686F04228, PP2243, SOC, SOCI, UBXD5
Gene Description
UBX domain protein 11
Omim ID
609151Gene Ontology
HyperlinkGene Summary
This gene encodes a protein with a divergent C-terminal UBX domain. The homologous protein in the rat interacts with members of the Rnd subfamily of Rho GTPases at the cell periphery through its C-terminal region. It also interacts with several heterotrimeric G proteins through their G-alpha subunits and promotes Rho GTPase activation. It is proposed to serve a bidirectional role in the promotion and inhibition of Rho activity through upstream signaling pathways. The 3' coding sequence of this gene contains a polymoprhic region of 24 nt tandem repeats. Several transcripts containing between 1.5 and five repeat units have been reported. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000003460|OTTHUMP00000003461|OTTHUMP00000003462|OTTHUMP00000003463|UBX domain containing 5|colorectal tumor-associated antigen-1|socius
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Interactome
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Publication Reference
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Large-scale cDNA transfection screening for genes related to cancer development and progression.
Wan D, Gong Y, Qin W, Zhang P, Li J, Wei L, Zhou X, Li H, Qiu X, Zhong F, He L, Yu J, Yao G, Jiang H, Qian L, Yu Y, Shu H, Chen X, Xu H, Guo M, Pan Z, Chen Y, Ge C, Yang S, Gu J.
PNAS 2004 Oct; 101(44):15724.
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Complete sequencing and characterization of 21,243 full-length human cDNAs.
Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K
Nature Genetics 2003 Dec; 36(1):40.
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Identification of a colorectal tumor-associated antigen (COA-1) recognized by CD4(+) T lymphocytes.
Maccalli C, Li YF, El-Gamil M, Rosenberg SA, Robbins PF.
Cancer Research 2003 Oct; 63(20):6735.
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Large-scale cDNA transfection screening for genes related to cancer development and progression.
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