MN1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of MN1.
Immunogen
A synthetic peptide corresponding to internal of human MN1.
Host
Rabbit
Reactivity
Human
Specificity
This antibody detects endogenous levels of total MN1 protein.
Form
Liquid
Recommend Usage
Western Blot (1:500-1:1000)
ELISA (1:40000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of extracts from COLO 205 cells, using MN1 polyclonal antibody (Cat # PAB17380).
Peptide "+" means "with peptide blocking". -
Gene Info — MN1
Entrez GeneID
4330Protein Accession#
Q10571Gene Name
MN1
Gene Alias
MGCR, MGCR1, MGCR1-PEN, dJ353E16.2
Gene Description
meningioma (disrupted in balanced translocation) 1
Gene Ontology
HyperlinkGene Summary
Meningioma 1 (MN1) contains two sets of CAG repeats. It is disrupted by a balanced translocation (4;22) in a meningioma, and its inactivation may contribute to meningioma 32 pathogenesis. [provided by RefSeq
Other Designations
OTTHUMP00000028743|bK437G10B.1 (meningioma (disrupted in balanced translocation) 1)|meningioma 1|meningioma (translocation balanced)|meningioma chromosome region 1|probable tumor suppressor protein MN1
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Interactome
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Disease
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Publication Reference
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The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, K
Genome Research 2004 Oct; 14(10B):2121.
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[The characteristics of different types of mRNA expressed in the human brain].
Dmitrenko VV, Garifulin OM, Shostak EA, Smikodub AI, Kavsan VM.
Tsitol Genet 1996 Sep; 30(5):41.
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Cloning and characterization of MN1, a gene from chromosome 22q11, which is disrupted by a balanced translocation in a meningioma.
Lekanne Deprez RH, Riegman PH, Groen NA, Warringa UL, van Biezen NA, Molijn AC, Bootsma D, de Jong PJ, Menon AG, Kley NA, et al..
Oncogene 1995 Apr; 10(8):1521.
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The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
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