HCFC1 polyclonal antibody
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using HCFC1 polyclonal antibody (Cat # PAB17367).
Peptide "+" means "with peptide blocking".
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of HCFC1.
Immunogen
A synthetic peptide corresponding to internal of human HCFC1.
Host
Rabbit
Reactivity
Human, Mouse
Specificity
This antibody detects endogenous levels of total HCFC1 protein.
Form
Liquid
Recommend Usage
Immunohistochemistry (1:50-1:100)
ELISA (1:40000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using HCFC1 polyclonal antibody (Cat # PAB17367).
Peptide "+" means "with peptide blocking". -
Gene Info — HCFC1
Entrez GeneID
3054Protein Accession#
P51610Gene Name
HCFC1
Gene Alias
CFF, HCF-1, HCF1, HFC1, MGC70925, VCAF
Gene Description
host cell factor C1 (VP16-accessory protein)
Omim ID
300019Gene Ontology
HyperlinkGene Summary
This gene is a member of the host cell factor family and encodes a protein with five Kelch repeats, a fibronectin-like motif, and six HCF repeats, each of which contains a highly specific cleavage signal. This nuclear coactivator is proteolytically cleaved at one of the six possible sites, resulting in the creation of an N-terminal chain and the corresponding C-terminal chain. The final form of this protein consists of noncovalently bound N- and C-terminal chains. The protein is involved in control of the cell cycle and transcriptional regulation during herpes simplex virus infection. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq
Other Designations
host cell factor 1
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Interactome
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Disease
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Publication Reference
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The cellular C1 factor of the herpes simplex virus enhancer complex is a family of polypeptides.
Kristie TM, Pomerantz JL, Twomey TC, Parent SA, Sharp PA.
The Journal of Biological Chemistry 1995 Mar; 270(9):4387.
Application：IF, GSA, WB-Ce, WB-Re, Human, 143 cells, HeLa cells, HepG2 cells, MRC-5 cells, Recombinant proteins.
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The VP16 accessory protein HCF is a family of polypeptides processed from a large precursor protein.
Wilson AC, LaMarco K, Peterson MG, Herr W.
Cell 1993 Jul; 74(1):115.
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Asthma, allergy and immunotherapy; a historical review: Part II.
S G Cohen, R Evans 3rd.
Allergy Proceedings 1992 Jan; 3(1):47.
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The cellular C1 factor of the herpes simplex virus enhancer complex is a family of polypeptides.
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