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Last updated: 2017/3/26
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ACTN2/ACTN3 polyclonal antibody

  • Catalog # : PAB17362
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of ACTN2/ACTN3.
  • Immunogen:
  • A synthetic peptide corresponding to N-terminus of human ACTN2/ACTN3.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • This antibody detects endogenous levels of total ACTN2/ACTN3 protein.
  • Form:
  • Liquid
  • Recommend Usage:
  • Western Blot (1:500-1:1000)
    Immunohistochemistry (1:50-1:100)
    Immunofluorescence (1:500-1:1000)
    ELISA (1:20000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of extracts from HeLa cells (Lane 1), HepG2 cells (Lane 2) and HUVEC cells (Lane 3 and lane 4), using ACTN2/ACTN3 polyclonal antibody (Cat # PAB17362).
    Peptide "+" means "with peptide blocking".
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry analysis of paraffin-embedded human skeletal muscle tissue using ACTN2/ACTN3 polyclonal antibody (Cat # PAB17362).
    Peptide "+" means "with peptide blocking".
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 88
  • Protein Accession#:
  • P35609 (Gene ID : 88);Q08043 (Gene ID : 89)
  • Gene Name:
  • ACTN2
  • Gene Alias:
  • CMD1AA
  • Gene Description:
  • actinin, alpha 2
  • Gene Summary:
  • Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. [provided by RefSeq
  • Other Designations:
  • F-actin cross-linking protein,OTTHUMP00000037963,alpha-actinin skeletal muscle
  • Gene Information
  • Entrez GeneID:
  • 89
  • Protein Accession#:
  • P35609 (Gene ID : 88);Q08043 (Gene ID : 89)
  • Gene Name:
  • ACTN3
  • Gene Alias:
  • MGC117002,MGC117005
  • Gene Description:
  • actinin, alpha 3
  • Gene Summary:
  • Alpha-actinin is an actin-binding protein with multiple roles in different cell types. This gene expression is limited to skeletal muscle. It is localized to the Z-disc and analogous dense bodies, where it helps to anchor the myofibrillar actin filaments [provided by RefSeq
  • Other Designations:
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