HOXD12 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of extracts from COLO 205 cells (Lane 1 and lane 3) treated with serum (20%, 15 mins), and HUVEC cells (Lane 2) treated with EGF (200 ng/ml, 15 mins), using HOXD12 polyclonal antibody (Cat # PAB17361).
Peptide "+" means "with peptide blocking".
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of HOXD12.
Immunogen
A synthetic peptide corresponding to internal of human HOXD12.
Host
Rabbit
Reactivity
Human, Mouse
Specificity
This antibody detects endogenous levels of total HOXD12 protein.
Form
Liquid
Recommend Usage
Western Blot (1:500-1:1000)
ELISA (1:5000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of extracts from COLO 205 cells (Lane 1 and lane 3) treated with serum (20%, 15 mins), and HUVEC cells (Lane 2) treated with EGF (200 ng/ml, 15 mins), using HOXD12 polyclonal antibody (Cat # PAB17361).
Peptide "+" means "with peptide blocking". -
Gene Info — HOXD12
Entrez GeneID
3238Protein Accession#
P35452Gene Name
HOXD12
Gene Alias
HOX4H
Gene Description
homeobox D12
Omim ID
142988Gene Ontology
HyperlinkGene Summary
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. The exact role of this gene has not been determined. [provided by RefSeq
Other Designations
Hox-4.7, mouse, homolog of|homeo box D12|homeobox protein Hox-D12
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Interactome
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Disease
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Publication Reference
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EVX2, a human homeobox gene homologous to the even-skipped segmentation gene, is localized at the 5' end of HOX4 locus on chromosome 2.
D'Esposito M, Morelli F, Acampora D, Migliaccio E, Simeone A, Boncinelli E.
Genomics 1991 May; 10(1):43.
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EVX2, a human homeobox gene homologous to the even-skipped segmentation gene, is localized at the 5' end of HOX4 locus on chromosome 2.
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