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Last updated: 2016/12/4
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ADRA2B polyclonal antibody

  • Catalog # : PAB17354
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of ADRA2B.
  • Immunogen:
  • A synthetic peptide corresponding to internal of human ADRA2B.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Specificity:
  • This antibody detects endogenous levels of total ADRA2B protein.
  • Form:
  • Liquid
  • Recommend Usage:
  • IImmunofluorescence (1:500-1:1000)
    ELISA (1:20000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescence analysis of HepG2 cells, using ADRA2B polyclonal antibody (Cat # PAB17354).
    Peptide "+" means "with peptide blocking".
  • Application Image
  • Gene Information
  • Entrez GeneID:
  • 151
  • Gene Name:
  • ADRA2B
  • Gene Alias:
  • ADRA2L1,ADRA2RL1,ADRARL1,ALPHA2BAR
  • Gene Description:
  • adrenergic, alpha-2B-, receptor
  • Gene Summary:
  • Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. This gene encodes the alpha2B subtype, which was observed to associate with eIF-2B, a guanine nucleotide exchange protein that functions in regulation of translation. A polymorphic variant of the alpha2B subtype, which lacks 3 glutamic acids from a glutamic acid repeat element, was identified to have decreased G protein-coupled receptor kinase-mediated phosphorylation and desensitization; this polymorphic form is also associated with reduced basal metabolic rate in obese subjects and may therefore contribute to the pathogenesis of obesity. This gene contains no introns in either its coding or untranslated sequences. [provided by RefSeq
  • Other Designations:
  • ADRA2B adrenergic, alpha-2B-, receptor,G-protein coupled receptor,adrenergic receptor alpha 2B,alpha-2-adrenergic receptor-like 1,alpha-2B-adrenergic receptor
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