TACC1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TACC1.
Immunogen
A synthetic peptide corresponding to N-terminus of human TACC1.
Host
Rabbit
Reactivity
Human, Mouse
Specificity
This antibody detects endogenous levels of total TACC1 protein.
Form
Liquid
Recommend Usage
Western Blot (1:500-1:1000)
Immunofluorescence (1:500-1:1000)
ELISA (1:10000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of extracts from K-562 cells, using TACC1 polyclonal antibody (Cat # PAB17344).
Peptide "+" means "with peptide blocking".Immunofluorescence
Immunofluorescence analysis of MCF-7 cells, using TACC1 polyclonal antibody (Cat # PAB17344).
Peptide "+" means "with peptide blocking". -
Gene Info — TACC1
Entrez GeneID
6867Protein Accession#
O75410Gene Name
TACC1
Gene Alias
DKFZp686K18126, Ga55, KIAA1103
Gene Description
transforming, acidic coiled-coil containing protein 1
Omim ID
605301Gene Ontology
HyperlinkGene Summary
This locus may represent a breast cancer candidate gene. It is located close to FGFR1 on a region of chromosome 8 that is amplified in some breast cancers. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
transforming, acidic coiled-coil containing protein 1 variant TACC1-B
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Interactome
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Disease
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Publication Reference
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Structure-function evolution of the transforming acidic coiled coil genes revealed by analysis of phylogenetically diverse organisms.
Still IH, Vettaikkorumakankauv AK, DiMatteo A, Liang P.
BMC Evolutionary Biology 2004 Jun; 4:16.
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Cloning of TACC1, an embryonically expressed, potentially transforming coiled coil containing gene, from the 8p11 breast cancer amplicon.
Still IH, Hamilton M, Vince P, Wolfman A, Cowell JK.
Oncogene 1999 Jul; 18(27):4032.
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Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.
Kikuno R, Nagase T, Ishikawa K, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O.
DNA Research 1999 Jun; 6(3):197.
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Structure-function evolution of the transforming acidic coiled coil genes revealed by analysis of phylogenetically diverse organisms.
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