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ZAK polyclonal antibody

  • Catalog # : PAB17320
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of ZAK.
  • Immunogen:
  • A synthetic peptide corresponding to residues surrounding serine 165 of human ZAK.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse
  • Specificity:
  • This antibody detects endogenous levels of total ZAK protein.
  • Form:
  • Liquid
  • Recommend Usage:
  • Western Blot (1:500-1:1000)
    ELISA (1:40000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • 1.
  • The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
    Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, KGenome Res. 2004 Oct;14(10B):2121-7.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of extracts from Jurkat cells, using ZAK polyclonal antibody (Cat # PAB17320).
    Peptide "+" means "with peptide blocking".
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Gene Name:
  • ZAK
  • Gene Alias:
  • AZK,MLK7,MLT,MLTK,MRK,mlklak
  • Gene Description:
  • sterile alpha motif and leucine zipper containing kinase AZK
  • Gene Summary:
  • This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
  • Other Designations:
  • MLK-like mitogen-activated protein triple kinase,MLK-related kinase,cervical cancer suppressor gene 4 protein,leucine zipper- and sterile alpha motif-containing kinase,mitogen-activated protein kinase kinase kinase MLT,mixed lineage kinase 7,mixed lineage
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