IL9R polyclonal antibody
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Specifications
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of IL9R.
Immunogen
A synthetic peptide corresponding to internal of human IL9R.
Host
Rabbit
Reactivity
Human
Specificity
This antibody detects endogenous levels of total IL9R protein.
Form
Liquid
Recommend Usage
Immunohistochemistry (1:50-1:100)
ELISA (1:40000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry analysis of paraffin-embedded human lymph node tissue using IL9R polyclonal antibody (Cat # PAB17312).
Peptide "+" means "with peptide blocking". -
Gene Info — IL9R
Entrez GeneID
3581Protein Accession#
Q01113Gene Name
IL9R
Gene Alias
CD129
Gene Description
interleukin 9 receptor
Omim ID
300007Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor, gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologic responses. This gene is located at the pseudoautosomal regions of X and Y chromosomes. Genetic studies suggested an association of this gene with the development of asthma. Multiple pseudogenes on chromosome 9, 10, 16, and 18 have been described. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000024332
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Interactomes
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Pathways
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Publication Reference
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Differentially regulated and evolved genes in the fully sequenced Xq/Yq pseudoautosomal region.
Ciccodicola A, D'Esposito M, Esposito T, Gianfrancesco F, Migliaccio C, Miano MG, Matarazzo MR, Vacca M, Franze A, Cuccurese M, Cocchia M, Curci A, Terracciano A, Torino A, Cocchia S, Mercadante G, Pannone E, Archidiacono N, Rocchi M, Schlessinger D, D'Urso M.
Human Molecular Genetics 2000 Feb; 9(3):395.
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The IL-9 receptor gene (IL9R): genomic structure, chromosomal localization in the pseudoautosomal region of the long arm of the sex chromosomes, and identification of IL9R pseudogenes at 9qter, 10pter, 16pter, and 18pter.
Kermouni A, Van Roost E, Arden KC, Vermeesch JR, Weiss S, Godelaine D, Flint J, Lurquin C, Szikora JP, Higgs DR, et al..
Genomics 1995 Sep; 29(2):371.
Application:WB-Ce, WB-Tr, Human, Mammalian cells.
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Isolation and characterization of the human interleukin-9 receptor gene.
Chang MS, Engel G, Benedict C, Basu R, McNinch J.
Blood 1994 Jun; 83(11):3199.
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Differentially regulated and evolved genes in the fully sequenced Xq/Yq pseudoautosomal region.
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