CD226 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of extracts from 293 cells, treated with PMA (125 ng/ml, 30 mins), using CD226 polyclonal antibody (Cat # PAB17304).
Peptide "+" means "with peptide blocking".
Immunofluorescence
Immunofluorescence analysis of HeLa cells, using CD226 polyclonal antibody (Cat # PAB17304).
Peptide "+" means "with peptide blocking".
-
Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CD226.
Immunogen
A synthetic peptide corresponding to residues surrounding serine 329 of human CD226.
Host
Rabbit
Reactivity
Human, Mouse
Specificity
This antibody detects endogenous levels of total CD226 protein.
Form
Liquid
Recommend Usage
Western Blot (1:500-1:1000)
Immunofluorescence (1:500-1:1000)
ELISA (1:5000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Cell lysate)
Western blot analysis of extracts from 293 cells, treated with PMA (125 ng/ml, 30 mins), using CD226 polyclonal antibody (Cat # PAB17304).
Peptide "+" means "with peptide blocking".Immunofluorescence
Immunofluorescence analysis of HeLa cells, using CD226 polyclonal antibody (Cat # PAB17304).
Peptide "+" means "with peptide blocking". -
Gene Info — CD226
Entrez GeneID
10666Protein Accession#
Q15762Gene Name
CD226
Gene Alias
DNAM-1, DNAM1, PTA1, TLiSA1
Gene Description
CD226 molecule
Omim ID
605397Gene Ontology
HyperlinkGene Summary
This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. [provided by RefSeq
Other Designations
CD226 antigen|DNAX accessory molecule-1|T lineage-specific activation antigen 1 antigen|adhesion glycoprotein|platelet and T cell activation antigen 1
-
Interactome
-
Pathway
-
Disease
-
Publication Reference
-
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, K
Genome Research 2004 Oct; 14(10B):2121.
-
Functional characterization of DNAM-1 (CD226) interaction with its ligands PVR (CD155) and nectin-2 (PRR-2/CD112).
Tahara-Hanaoka S, Shibuya K, Onoda Y, Zhang H, Yamazaki S, Miyamoto A, Honda S, Lanier LL, Shibuya A.
International Immunology 2004 Apr; 16(4):533.
Application：Flow Cyt, Func, Human, BW5147, EBV-B, H9, HOS, RD, T cells, U87MG, U937 cells .
-
DNAM-1, a novel adhesion molecule involved in the cytolytic function of T lymphocytes.
Shibuya A, Campbell D, Hannum C, Yssel H, Franz-Bacon K, McClanahan T, Kitamura T, Nicholl J, Sutherland GR, Lanier LL, Phillips JH.
Immunity 1996 Jun; 4(6):573.
-
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com