TLK1 polyclonal antibody
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More Files
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Specifications
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TLK1.
Immunogen
A synthetic peptide corresponding to internal of human TLK1.
Host
Rabbit
Reactivity
Human, Mouse
Specificity
This antibody detects endogenous levels of total TLK1 protein.
Form
Liquid
Recommend Usage
Immunofluorescence (1:500-1:1000)
ELISA (1:5000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunofluorescence
Immunofluorescence analysis of COS-7 cells, using TLK1 polyclonal antibody (Cat # PAB17299).
Peptide "+" means "with peptide blocking". -
Gene Info — TLK1
Entrez GeneID
9874Protein Accession#
Q9Y4F6Gene Name
TLK1
Gene Alias
KIAA0137, PKU-beta
Gene Description
tousled-like kinase 1
Omim ID
608438Gene Ontology
HyperlinkGene Summary
The Tousled-like kinases, first described in Arabidopsis, are nuclear serine/threonine kinases that are potentially involved in the regulation of chromatin assembly.[supplied by OMIM
Other Designations
SNARE protein kinase SNAK|serine threonine protein kinase
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Interactomes
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Publication Reference
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Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.
Daisuke Nakajima, Noriko Okazaki, Hisashi Yamakawa, Reiko Kikuno, Osamu Ohara, Takahiro Nagase.
DNA Research 2002 Jun; 9(3):99.
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Mammalian homologues of the plant Tousled gene code for cell-cycle-regulated kinases with maximal activities linked to ongoing DNA replication.
Sillje HH, Takahashi K, Tanaka K, Van Houwe G, Nigg EA.
The EMBO Journal 1999 Oct; 18(20):5691.
Application:IF, IP, KA, WB-Ce, WB-Re, Human, HeLa cells, Recombinant protein, U2-OS cells.
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cDNA cloning and chromosomal mapping of genes encoding novel protein kinases termed PKU-alpha and PKU-beta, which have nuclear localization signal.
A Yamakawa, Y Kameoka, K Hashimoto, Y Yoshitake, K Nishikawa, K Tanihara, T Date.
Gene 1997 Nov; 202(1-2):193.
Application:IF, Monkey, COS-1 cells.
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Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.
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