PLCB3 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of PLCB3.
Immunogen
A synthetic peptide corresponding to internal of human PLCB3.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
This antibody detects endogenous levels of total PLCB3 protein.
Form
Liquid
Recommend Usage
Immunohistochemistry (1:50-1:100)
Immunofluorescence (1:500-1:1000)
ELISA (1:5000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using PLCB3 polyclonal antibody (Cat # PAB17298).
Peptide "+" means "with peptide blocking".Immunofluorescence
Immunofluorescence analysis of A-549 cells, using PLCB3 polyclonal antibody (Cat # PAB17298).
Peptide "+" means "with peptide blocking". -
Gene Info — PLCB3
Entrez GeneID
5331Protein Accession#
Q01970Gene Name
PLCB3
Gene Alias
FLJ37084
Gene Description
phospholipase C, beta 3 (phosphatidylinositol-specific)
Omim ID
600230Gene Ontology
HyperlinkGene Summary
PLCB3 plays an important role in initiating receptor-mediated signal transduction. Activation of PLC takes place in many cells as a response to stimulation by hormones, growth factors, neurotransmitters, and other ligands (Lagercrantz et al., 1995 [PubMed 7607669]).[supplied by OMIM
Other Designations
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Interactome
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Pathway
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Disease
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Publication Reference
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Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M.
Cell 2006 Nov; 127(3):635.
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Large-scale characterization of HeLa cell nuclear phosphoproteins.
Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villen J, Li J, Cohn MA, Cantley LC, Gygi SP.
PNAS 2004 Aug; 101(33):12130.
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Structural organization and expression of the human phosphatidylinositol-specific phospholipase C beta-3 gene.
Mazuruk K, Schoen TJ, Chader GJ, Rodriguez IR.
Biochemical and Biophysical Research Communications 1995 Jul; 212(1):190.
Application:WB-Ti, Human, Human tissues.
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Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
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