FCGR2B polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of FCGR2B.
Immunogen
A synthetic peptide corresponding to residues surrounding serine 363 of human FCGR2B.
Host
Rabbit
Reactivity
Human
Specificity
This antibody detects endogenous levels of total FCGR2B protein.
Form
Liquid
Recommend Usage
Western Blot (1:500-1:1000)
ELISA (1:5000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of extracts from Jurkat cells, treated with PMA (125 ng/ml, 30 mins), using FCGR2B polyclonal antibody (Cat # PAB17294).
Peptide "+" means "with peptide blocking". -
Gene Info — FCGR2B
Entrez GeneID
2213Protein Accession#
P31994Gene Name
FCGR2B
Gene Alias
CD32, CD32B, FCG2, FCGR2, IGFR2
Gene Description
Fc fragment of IgG, low affinity IIb, receptor (CD32)
Gene Ontology
HyperlinkGene Summary
low affinity IIb
Other Designations
Fc fragment of IgG, low affinity II, receptor for (CD32)|Fc fragment of IgG, low affinity IIb, receptor for (CD32)|Fc gamma RIIb|OTTHUMP00000032379
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Interactome
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Pathway
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Disease
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Publication Reference
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A regulatory role for Fcgamma receptors CD16 and CD32 in the development of murine B cells.
de Andres B, Mueller AL, Verbeek S, Sandor M, Lynch RG.
Blood 1998 Oct; 92(8):2823.
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Expression of functional CD32 molecules on human NK cells is determined by an allelic polymorphism of the FcgammaRIIC gene.
Metes D, Ernst LK, Chambers WH, Sulica A, Herberman RB, Morel PA.
Blood 1998 Apr; 91(7):2369.
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Dermal microvascular endothelial cells express CD32 receptors in vivo and in vitro.
Groger M, Sarmay G, Fiebiger E, Wolff K, Petzelbauer P.
Journal of Immunology 1996 Feb; 156(4):1549.
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A regulatory role for Fcgamma receptors CD16 and CD32 in the development of murine B cells.
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