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Last updated: 2016/12/4
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GRLF1 polyclonal antibody

  • Catalog # : PAB17285
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of GRLF1.
  • Immunogen:
  • A synthetic peptide corresponding to internal of human GRLF1.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • This antibody detects endogenous levels of total GRFL1 protein.
  • Form:
  • Liquid
  • Recommend Usage:
  • Immunohistochemistry (1:50-1:100)
    ELISA (1:40000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using GRLF1 polyclonal antibody (Cat # PAB17285).
    Peptide "+" means "with peptide blocking".
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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  • Gene Information
  • Entrez GeneID:
  • 2909
  • Gene Name:
  • GRLF1
  • Gene Alias:
  • GRF-1,KIAA1722,MGC10745,P190-A,P190A,p190RhoGAP
  • Gene Description:
  • glucocorticoid receptor DNA binding factor 1
  • Gene Summary:
  • The human glucocorticoid receptor DNA binding factor, which associates with the promoter region of the glucocorticoid receptor gene (hGR gene), is a repressor of glucocorticoid receptor transcription. The amino acid sequence deduced from the cDNA sequences show the presence of three sequence motifs characteristic of a zinc finger and one motif suggestive of a leucine zipper in which 1 cysteine is found instead of all leucines. The GRLF1 enhances the homologous down-regulation of wild-type hGR gene expression. Biochemical analysis suggests that GRLF1 interaction is sequence specific and that transcriptional efficacy of GRLF1 is regulated through its interaction with specific sequence motif. The level of expression is regulated by glucocorticoids. [provided by RefSeq
  • Other Designations:
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