MS4A1 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of MS4A1.
Immunogen
A synthetic peptide corresponding to human MS4A1.
Sequence
CQDQESSPIENDSSP
Host
Goat
Theoretical MW (kDa)
33.1
Reactivity
Human
Specificity
Please note that both reported variants (NP_068769.2 and NP_690605.1) encode the same protein.
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:4000)
Western Blot (0.003-0.01 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
MS4A1 polyclonal antibody (Cat # PAB17275) (0.003 ug/mL) staining of human lymph lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — MS4A1
Entrez GeneID
931Protein Accession#
NP_068769.2;NP_690605.1.Gene Name
MS4A1
Gene Alias
B1, Bp35, CD20, LEU-16, MGC3969, MS4A2, S7
Gene Description
membrane-spanning 4-domains, subfamily A, member 1
Omim ID
112210Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein. [provided by RefSeq
Other Designations
B-lymphocyte cell-surface antigen B1|CD20 antigen|CD20 receptor
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Interactome
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Pathway
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Disease
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Publication Reference
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Analysis of two cDNA clones encoding the B lymphocyte antigen CD20 (B1, Bp35), a type III integral membrane protein.
Stamenkovic I, Seed B.
The Journal of Experimental Medicine 1988 Jun; 167(6):1975.
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Analysis of two cDNA clones encoding the B lymphocyte antigen CD20 (B1, Bp35), a type III integral membrane protein.
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