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Last updated: 2017/6/18
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GJB6 polyclonal antibody

  • Catalog # : PAB17269
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of GJB6.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids at internal region of human GJB6.
  • Sequence:
  • C-RSKRAQTQKNHPNH
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 30.4
  • Specificity:
  • Reported variants represent identical protein: NP_006774.2, NP_001103691.1, NP_001103689.1, NP_001103690.1
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Recommend Usage:
  • ELISA (1:16000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • ELISA
  • Application Image
  • ELISA
  • Gene Information
  • Gene Name:
  • GJB6
  • Gene Alias:
  • CX30,DFNA3,ED2,EDH,HED
  • Gene Description:
  • gap junction protein, beta 6, 30kDa
  • Gene Summary:
  • Gap junctions allow the transport of ions and metabolites between the cytoplasm of adjacent cells. They are formed by two hemichannels, made up of six connexin proteins assembled in groups. Each connexin protein has four transmembrane segments, two extracellular loops, a cytoplasmic loop formed between the two inner transmembrane segments, and the N- and C-terminus both being in the cytoplasm. The specificity of the gap junction is determined by which connexin proteins comprise the hemichannel. In the past, connexin protein names were based on their molecular weight, however the new nomenclature uses sequential numbers based on which form (alpha or beta) of the gap junction is present. This gene encodes one of the connexin proteins. Mutations in this gene have been found in some forms of deafness and in some families with hidrotic ectodermal dysplasia. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000018096,OTTHUMP00000176870,OTTHUMP00000176871,OTTHUMP00000176872,connexin 30,ectodermal dysplasia 2, hidrotic (Clouston syndrome),gap junction protein, beta 6,gap junction protein, beta 6 (connexin 30)
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