GJC3 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of GJC3.
Immunogen
A synthetic peptide corresponding to amino acids at internal region of human GJC3.
Sequence
C-LTSESTRRHKKATDS
Host
Goat
Theoretical MW (kDa)
31.3
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:32000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — GJC3
Entrez GeneID
349149Protein Accession#
NP_853516.1Gene Name
GJC3
Gene Alias
CX30.2, CX31.3, Cx29, GJE1
Gene Description
gap junction protein, gamma 3, 30.2kDa
Gene Ontology
HyperlinkGene Summary
Connexins, such as GJC3, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits (Sohl et al., 2003 [PubMed 12881038]).[supplied by OMIM
Other Designations
connexin 29|connexin 30.2|connexin 31.3|gap junction protein, epsilon 1, 29kDa
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Interactome
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Disease
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Publication Reference
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Human oligodendrocytes express Cx31.3: function and interactions with Cx32 mutants.
Sargiannidou I, Ahn M, Enriquez AD, Peinado A, Reynolds R, Abrams C, Scherer SS, Kleopa KA.
Neurobiology of Disease 2008 Feb; 30(2):221.
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Human oligodendrocytes express Cx31.3: function and interactions with Cx32 mutants.
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