FGL1 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of FGL1.
Immunogen
A synthetic peptide corresponding to amino acids at internal region of human FGL1.
Sequence
C-ETRVKQQQVKIKQ
Host
Goat
Theoretical MW (kDa)
36.4
Reactivity
Human
Specificity
Reported variants represent identical protein: NP_963846.1, NP_963847.1, NP_671736.2, NP_004458.3
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:16000)
Western Blot (0.1-0.3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
FGL1 polyclonal antibody (Cat # PAB17261) (0.1 ug/mL) staining of human liver lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — FGL1
Entrez GeneID
2267Protein Accession#
NP_004458.3Gene Name
FGL1
Gene Alias
HFREP1, HP-041, LFIRE1, MGC12455
Gene Description
fibrinogen-like 1
Omim ID
605776Gene Ontology
HyperlinkGene Summary
Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000122468|hepassocin|hepatocellular carcinoma-related sequence|hepatocyte-derived fibrinogen-related protein 1
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Interactome
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Disease
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Publication Reference
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Fibrinogen-like protein 1, a hepatocyte derived protein is an acute phase reactant.
Liu Z, Ukomadu C.
Biochemical and Biophysical Research Communications 2007 Nov; 365(4):729.
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Fibrinogen-like protein 1, a hepatocyte derived protein is an acute phase reactant.
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