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TET2 polyclonal antibody 

  • Catalog # : PAB17253
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of TET2.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids at internal region of human TET2.
  • Sequence:
  • C-PHPQSNNDQQREGSF
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 224, 130
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is expected to recognize both reported isoforms (NP_001120680.1; NP_060098.3).
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Recommend Usage:
  • ELISA (1:16000)
    Flow Cytometry (10 ug/mL)
    Immunohistochemistry (2-6 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • 1.
  • Acquired mutations in TET2 are common in myelodysplastic syndromes.
    Langemeijer SM, Kuiper RP, Berends M, Knops R, Aslanyan MG, Massop M, Stevens-Linders E, van Hoogen P, van Kessel AG, Raymakers RA, Kamping EJ, Verhoef GE, Verburgh E, Hagemeijer A, Vandenberghe P, de Witte T, van der Reijden BA, Jansen JH.Nat Genet. 2009 Jul;41(7):838-42. Epub 2009 May 31.
  • Applications
  • Enzyme-linked Immunoabsorbent Assay
  • Flow Cytometry
  • Flow Cytometry
  • TET2 polyclonal antibody (Cat # PAB17253) Flow cytometric analysis of paraformaldehyde fixed A431 cells (blue line), permeabilized with 0.5% Triton. Primary incubation 1hr (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (1 ug/mL). IgG control: Unimmunized goat IgG (black line) followed by Alexa Fluor 488 secondary antibody.
  • Application Image
  • Enzyme-linked Immunoabsorbent Assay
  • Gene Information
  • Protein Accession#:
  • NP_001120680.1;NP_060098.3
  • Gene Name:
  • TET2
  • Gene Alias:
  • FLJ20032,KIAA1546,MGC125715
  • Gene Description:
  • tet oncogene family member 2
  • Other Designations:
  • OTTHUMP00000161869
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