SUMF1 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of SUMF1.
Immunogen
A synthetic peptide corresponding to amino acids at internal region of human SUMF1.
Sequence
C-ETLNPKGPPSGKDR
Host
Goat
Theoretical MW (kDa)
40.6
Reactivity
Human, Mouse
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:16000)
Western Blot (0.5-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
SUMF1 polyclonal antibody (Cat # PAB17245) (1 ug/mL) staining of mouse pancreas lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — SUMF1
Entrez GeneID
285362Protein Accession#
NP_877437.2Gene Name
SUMF1
Gene Alias
AAPA3037, FGE, MGC131853, MGC150436
Gene Description
sulfatase modifying factor 1
Gene Ontology
HyperlinkGene Summary
This gene encodes an enzyme that catalyzes the hydrolysis of sulfate esters by oxidizing a cysteine residue in the substrate sulfatase to an active site 3-oxoalanine residue, which is also known as C-alpha-formylglycine. Mutations in this gene cause multiple sulfatase deficiency, a lysosomal storage disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
C-alpha-formylglycine-generating enzyme|OTTHUMP00000115300
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Interactome
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Disease
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Publication Reference
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Characterization of the arylsulfatase I (ARSI) gene preferentially expressed in the human retinal pigment epithelium cell line ARPE-19.
Oshikawa M, Usami R, Kato S.
Molecular Vision 2009 Mar; 15:482.
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Characterization of the arylsulfatase I (ARSI) gene preferentially expressed in the human retinal pigment epithelium cell line ARPE-19.
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