DSG1 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
DSG1 polyclonal antibody (Cat # PAB17239) (3.8 ug/mL) staining of paraffin embedded human skin. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
-
Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of DSG1.
Immunogen
A synthetic peptide corresponding to internal region of human DSG1.
Sequence
C-YTTSDTLKPSVHVHD
Host
Goat
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:32000)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (4-6 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
DSG1 polyclonal antibody (Cat # PAB17239) (3.8 ug/mL) staining of paraffin embedded human skin. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.Enzyme-linked Immunoabsorbent Assay
-
Gene Info — DSG1
Entrez GeneID
1828Protein Accession#
NP_001933.2Gene Name
DSG1
Gene Alias
CDHF4, DG1, DSG
Gene Description
desmoglein 1
Gene Ontology
HyperlinkGene Summary
Desmosomes are cell-cell junctions between epithelial, myocardial and certain other cell types. Desmoglein 1 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. The protein encoded by this gene has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus foliaceus. [provided by RefSeq
Other Designations
desmosomal glycoprotein 1|pemphigus foliaceus antigen
-
Interactome
-
Disease
-
Publication Reference
-
Structural analysis and expression of human desmoglein: a cadherin-like component of the desmosome.
Nilles LA, Parry DA, Powers EE, Angst BD, Wagner RM, Green KJ.
Journal of Cell Science 1991 Aug; 99 ( Pt 4):809.
-
Structural analysis and expression of human desmoglein: a cadherin-like component of the desmosome.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com