TREML1 polyclonal antibody
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More Files
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Western Blot (Tissue lysate)
TREML1 polyclonal antibody (Cat # PAB17232) staining (0.5 ug/mL) of human bone marrow lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of TREML1.
Immunogen
A synthetic peptide corresponding to human TREML1.
Sequence
CGPAQNPPNNQTPS
Host
Goat
Theoretical MW (kDa)
32.7
Reactivity
Human
Specificity
This antibody may cross-react with mouse TREML1 (GeneID: 71326; MW: 34.28 KDa).
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:2000)
Western Blot (0.3-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
TREML1 polyclonal antibody (Cat # PAB17232) staining (0.5 ug/mL) of human bone marrow lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — TREML1
Entrez GeneID
340205Protein Accession#
NP_835468.1Gene Name
TREML1
Gene Alias
GLTL1825, MGC119173, PRO3438, TLT-1, TLT1, dJ238O23.3
Gene Description
triggering receptor expressed on myeloid cells-like 1
Omim ID
609714Gene Ontology
HyperlinkGene Summary
TREML1 is located in a gene cluster on chromosome 6 with the single Ig variable (IgV) domain activating receptors TREM1 (MIM 605085) and TREM2 (MIM 605086), but it has distinct structural and functional properties. TREML1 enhances calcium signaling in an SHP2 (PTPN11; MIM 176876)-dependent manner (Allcock et al., 2003 [PubMed 12645956]; Barrow et al., 2004 [PubMed 15128762]).[supplied by OMIM
Other Designations
OTTHUMP00000017858|TREM-like transcript 1
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Publication Reference
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Phenotypic heterogeneity in the Gray platelet syndrome extends to the expression of TREM family member, TLT-1.
Nurden AT, Nurden P, Bermejo E, Combrie R, McVicar DW, Washington AV.
Research and Practice in Thrombosis and Haemostasis 2008 Jul; 100(1):45.
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Phenotypic heterogeneity in the Gray platelet syndrome extends to the expression of TREM family member, TLT-1.
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