MDFI polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of MDFI.
Immunogen
A synthetic peptide corresponding to amino acids at internal region of human MDFI.
Sequence
C-SKSTTSQIPLQAQED
Host
Goat
Theoretical MW (kDa)
25
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:16000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — MDFI
Entrez GeneID
4188Protein Accession#
NP_005577.1Gene Name
MDFI
Gene Alias
I-MF, I-mfa
Gene Description
MyoD family inhibitor
Omim ID
604971Gene Ontology
HyperlinkGene Summary
This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures. [provided by RefSeq
Other Designations
OTTHUMP00000016375|OTTHUMP00000196414|inhibitor of MyoD family a
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Interactome
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Publication Reference
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Inhibitor of myogenic family, a novel suppressor of store-operated currents through an interaction with TRPC1.
Ma R, Rundle D, Jacks J, Koch M, Downs T, Tsiokas L.
The Journal of Biological Chemistry 2003 Oct; 278(52):52763.
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Inhibitor of myogenic family, a novel suppressor of store-operated currents through an interaction with TRPC1.
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