NEBL polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of NEBL.
Immunogen
A synthetic peptide corresponding to amino acids at internal region of human NEBL.
Sequence
C-ELQRLKRTQE
Host
Goat
Theoretical MW (kDa)
116, 31.2
Specificity
This antibody is expected to recognize isoform 2 and isoform 3 (NP_998734.1; NP_001166955.1) only, but does not recognize isoform 1 (NP_006384.1).
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:4000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — NEBL
Entrez GeneID
10529Protein Accession#
NP_998734.1;NP_001166955.1Gene Name
NEBL
Gene Alias
FLJ53769, LNEBL, MGC119746, MGC119747, bA56H7.1
Gene Description
nebulette
Omim ID
605491Gene Ontology
HyperlinkGene Summary
actin-binding Z-disc protein|OTTHUMP00000019268|actin-binding Z-disk protein
Other Designations
LIM-nebulette|NEBL, actin-binding Z-disc protein|OTTHUMP00000019268|actin-binding Z-disk protein
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Interactome
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Disease
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Publication Reference
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The nebulette repeat domain is necessary for proper maintenance of tropomyosin with the cardiac sarcomere.
Bonzo JR, Norris AA, Esham M, Moncman CL.
Experimental Cell Research 2008 Sep; 314(19):3519.
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The nebulette repeat domain is necessary for proper maintenance of tropomyosin with the cardiac sarcomere.
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