Formalin-fixed and paraffin-embedded human cancer tissue reacted with ISG15 polyclonal antibody (Cat # PAB1720) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma.
ISG15 is a ubiquitin-like protein that becomes conjugated to many cellular proteins upon activation by interferon-alpha (IFNA; MIM 147660) and -beta (IFNB; MIM 147640) (Zhao et al., 2005 [PubMed 16009940]).[supplied by OMIM
OTTHUMP00000038464,interferon, alpha-inducible protein (clone IFI-15K),interferon-induced 17-kDa/15-kDa protein,interferon-stimulated protein, 15 kDa,ubiquitin cross-reactive protein