Western blot analysis of human S100A3 in hair extracts from 3 individual female. Lane 1 : base of hair from A. S. Lane 2 : tip of hair from A. S. Lane 3 : base of hair from M. S. Lane 4 : tip of hair from M. S. Lane 5 : base of hair from Y. K. Lane 6 : tip of hair from Y. K.
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein has the highest content of cysteines of all S100 proteins, has a high affinity for Zinc, and is highly expressed in human hair cuticle. The precise function of this protein is unknown. [provided by RefSeq
OTTHUMP00000015474,OTTHUMP00000032963,S100 calcium-binding protein A3