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Last updated: 2016/10/16
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COX4I1/COX4I2 polyclonal antibody

  • Catalog # : PAB17042
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of COX4I1/COX4I2.
  • Immunogen:
  • A synthetic peptide corresponding to human COX4I1/COX4I2.
  • Sequence:
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 19.6
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Recommend Usage:
  • ELISA (1:2000)
    Western Blot (1-3 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • COX4I1/COX4I2 polyclonal antibody (Cat # PAB17042) (1 ug/mL) staining of human skeletal muscle lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 1327
  • Gene Name:
  • COX4I1
  • Gene Alias:
  • COX4,COXIV,MGC72016
  • Gene Description:
  • cytochrome c oxidase subunit IV isoform 1
  • Gene Summary:
  • Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. [provided by RefSeq
  • Other Designations:
  • -
  • Gene Information
  • Gene Name:
  • COX4I2
  • Gene Alias:
  • COX4,COX4-2,COX4B,COX4L2,COXIV-2,dJ857M17.2
  • Gene Description:
  • cytochrome c oxidase subunit IV isoform 2 (lung)
  • Gene Summary:
  • Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes isoform 2 of subunit IV. Isoform 1 of subunit IV is encoded by a different gene, however, the two genes show a similar structural organization. Subunit IV is the largest nuclear encoded subunit which plays a pivotal role in COX regulation. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000030533,cytochrome c oxidase subunit IV isoform 2,cytochrome c oxidase subunit IV-like 2
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