CLEC4C polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
CLEC4C polyclonal antibody (Cat # PAB17024) (1 ug/mL) staining of human spleen lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of CLEC4C.
Immunogen
A synthetic peptide corresponding to human CLEC4C.
Sequence
QSWTKSQKNCSV
Host
Goat
Theoretical MW (kDa)
25.0, 21.5
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:8000)
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
CLEC4C polyclonal antibody (Cat # PAB17024) (1 ug/mL) staining of human spleen lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — CLEC4C
Entrez GeneID
170482Protein Accession#
NP_569708.1;NP_987099.1Gene Name
CLEC4C
Gene Alias
BDCA2, CD303, CLECSF11, CLECSF7, DLEC, HECL, MGC125789, MGC125791, MGC125792, MGC125793, PRO34150
Gene Description
C-type lectin domain family 4, member C
Omim ID
606677Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may play a role in dendritic cell function. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq
Other Designations
C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 11|C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 7|C-type lectin domain family 4, member C, isoform 1|blood dendritic cell anti
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Interactome
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Publication Reference
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TLR9/TLR7-triggered downregulation of BDCA2 expression on human plasmacytoid dendritic cells from healthy individuals and lupus patients.
Wu P, Wu J, Liu S, Han X, Lu J, Shi Y, Wang J, Lu L, Cao X.
Clinical Immunology (Orlando, Fla.) 2008 Oct; 29(1):40.
Application：Func, Human, Plasmacytoid dendritic cells from SLE patients.
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TLR9/TLR7-triggered downregulation of BDCA2 expression on human plasmacytoid dendritic cells from healthy individuals and lupus patients.
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