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Last updated: 2017/12/10
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FYN (phospho Y530) polyclonal antibody

  • Catalog # : PAB16971
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic phosphopeptide of FYN.
  • Immunogen:
  • Synthetic phosphopeptide corresponding to residues surrounding Y530 of human FYN.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • This antibody detects endogenous levels of FYN only when phosphorylated at tyrosine 530.
  • Form:
  • Liquid
  • Recommend Usage:
  • Immunohistochemistry (1:50-1:100)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 20 mM PBS, 0.15 M NaCl, pH 7.2 (0.01% sodium azide)
  • Storage Instruction:
  • Store at 4°C for three months. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • 1.
  • Signaling networks assembled by oncogenic EGFR and c-Met.
    Guo A, Villen J, Kornhauser J, Lee KA, Stokes MP, Rikova K, Possemato A, Nardone J, Innocenti G, Wetzel R, Wang Y, MacNeill J, Mitchell J, Gygi SP, Rush J, Polakiewicz RD, Comb MJ.Proc Natl Acad Sci U S A. 2008 Jan 15;105(2):692-7. Epub 2008 Jan 7.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using FYN (phospho Tyr530) polyclonal antibody (Cat # PAB16971).
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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  • Gene Information
  • Entrez GeneID:
  • 2534
  • Gene Name:
  • FYN
  • Gene Alias:
  • MGC45350,SLK,SYN
  • Gene Description:
  • FYN oncogene related to SRC, FGR, YES
  • Gene Summary:
  • This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist. [provided by RefSeq
  • Other Designations:
  • OKT3-induced calcium influx regulator,OTTHUMP00000017914,OTTHUMP00000017915,OTTHUMP00000017917,c-syn protooncogene,protein-tyrosine kinase fyn,proto-oncogene tyrosine-protein kinase fyn,src-like kinase,src/yes-related novel,tyrosine kinase p59fyn(T)
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