Western blot analysis of extracts from NIH/3T3 cells treated with using Serum. Lane 1 : Using FOXO3 (phospho S253) polyclonal antibody (Cat # PAB16950). Lane 2 : Using the same antibody preincubated with synthesized peptide.
This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq
Other Designations:
OTTHUMP00000016944,forkhead box O3A,forkhead homolog (rhabdomyosarcoma) like 1,forkhead, Drosophila, homolog of, in rhabdomyosarcoma-like 1