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Last updated: 2018/5/27
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PRDM1 polyclonal antibody

  • Catalog # : PAB16909
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of PRDM1 .
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus of human PRDM1 .
  • Host:
  • Rabbit
  • Reactivity:
  • Dog, Human, Mouse, Rat
  • Form:
  • Liquid
  • Recommend Usage:
  • ELISA (1:65000-1:80000)
    Western Blot (1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 20 mM KH2PO4, 150 mM NaCl, pH 7.2 (0.01% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot
  • Western Blot
  • Western blots using PRDM1 polyclonal antibody (Cat # PAB16909) show detection of overexpressed PRDM1 in whole transfected Raji cell lysate (Lane 2) at ~88kDa. Lane 1 shows mock transfection in whole Raji cell lysate. Detection of endogenous PRDM1 (Lane 4) is illustrated in human plasma cell nuclear extract, but not in Raji whole cell nuclear extract (Lane 3). The identity of the lower dark band at ~50-60kDa is unknown. Primary antibody was used at a 1 : 1000 dilution in 5% PBS-Tween.
    Personal communication, Hyesuk Yoon and Jerry Boss, Emory University, Atlanta, GA.
  • Application Image
  • Gene Information
  • Entrez GeneID:
  • 639
  • Gene Name:
  • PRDM1
  • Gene Alias:
  • BLIMP1,MGC118922,MGC118923,MGC118924,MGC118925,PRDI-BF1
  • Gene Description:
  • PR domain containing 1, with ZNF domain
  • Gene Summary:
  • This gene encodes a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported. [provided by RefSeq
  • Other Designations:
  • B-lymphocyte-induced maturation protein 1,OTTHUMP00000016918,PR-domain zinc finger protein 1,PRDI-binding factor-1,beta-interferon gene positive-regulatory domain I binding factor,positive regulatory domain I-binding factor 1
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