TMEM173 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TMEM173.
Immunogen
A synthetic peptide corresponding to C-terminus 17 amino acids of human TMEM173.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Recommend Usage
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for up to one year.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of TMEM173 in A-20 cell lysate with TMEM173 polyclonal antibody (Cat # PAB16794) at (A) 1 and (B) 2 ug/mL .Immunocytochemistry
Immunocytochemistry of TMEM173 in A-20 cells with TMEM173 polyclonal antibody (Cat # PAB16794) at 5 ug/mL .Enzyme-linked Immunoabsorbent Assay
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Gene Info — TMEM173
Entrez GeneID
340061Protein Accession#
NP_938023Gene Name
TMEM173
Gene Alias
FLJ38577, MITA, MPYS, STING
Gene Description
transmembrane protein 173
Gene Ontology
HyperlinkOther Designations
N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner|mitochondrial mediator of IRF3 activation|stimulator of interferon genes
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Interactome
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Disease
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Publication Reference
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The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation.
Zhong B, Yang Y, Li S, Wang YY, Li Y, Diao F, Lei C, He X, Zhang L, Tien P, Shu HB.
Immunity 2008 Oct; 29(4):538.
Application:WB-Tr, Human, A-549, HEK 293 cells.
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MPYS, a novel membrane tetraspanner, is associated with major histocompatibility complex class II and mediates transduction of apoptotic signals.
Jin L, Waterman PM, Jonscher KR, Short CM, Reisdorph NA, Cambier JC.
Molecular and Cellular Biology 2008 Aug; 28(16):5014.
Application:IP, WB, Mouse, K46 cells.
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The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation.
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