ZCRB1 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of ZCRB1 in Raji cell lysate with ZCRB1 polyclonal antibody (Cat # PAB16765) at (A) 1 and (B) 2 ug/mL .
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of ZCRB1.
Immunogen
A synthetic peptide corresponding to C-terminus 17 amino acids of human ZCRB1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of ZCRB1 in Raji cell lysate with ZCRB1 polyclonal antibody (Cat # PAB16765) at (A) 1 and (B) 2 ug/mL .Enzyme-linked Immunoabsorbent Assay
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Gene Info — ZCRB1
Entrez GeneID
85437Protein Accession#
NP_149105Gene Name
ZCRB1
Gene Alias
MADP-1, MADP1, MGC26805, RBM36, ZCCHC19
Gene Description
zinc finger CCHC-type and RNA binding motif 1
Omim ID
610750Gene Ontology
HyperlinkGene Summary
Pre-mRNA splicing is catalyzed by the spliceosome. U12-type spliceosome binds U12-type pre-mRNAs and recognizes the 5' splice site and branch-point sequence. U11 and U12 snRNPs are components of U12-type spliceosome and function as a molecular bridge connecting both ends of the intron. The protein encoded by this gene contains a RNA recognition motif. It was identified as one of the protein components of U11/U12 snRNPs. This protein and many other U11/U12 snRNP proteins are highly conserved in organisms known to contain U12-type introns. These proteins have been shown to be essential for cell viability, suggesting the key roles in U12-type splicing. [provided by RefSeq
Other Designations
U11/U12 snRNP 31K
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Interactome
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Publication Reference
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Proteomic identification of C/EBP-DBD multiprotein complex: JNK1 activates stem cell regulator C/EBPalpha by inhibiting its ubiquitination.
Trivedi AK, Bararia D, Christopeit M, Peerzada AA, Singh SM, Kieser A, Hiddemann W, Behre HM, Behre G.
Oncogene 2007 Mar; 26(12):1789.
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Isolation, expression, and characterization of the human ZCRB1 gene mapped to 12q12.
Wang H, Gao MX, Li L, Wang B, Hori N, Sato K.
Genomics 2007 Jan; 89(1):59.
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The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome.
Will CL, Schneider C, Hossbach M, Urlaub H, Rauhut R, Elbashir S, Tuschl T, Luhrmann R.
RNA 2004 Jun; 10(6):929.
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Proteomic identification of C/EBP-DBD multiprotein complex: JNK1 activates stem cell regulator C/EBPalpha by inhibiting its ubiquitination.
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