AFAP1L2 polyclonal antibody
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of AFAP1L2.
Immunogen
A synthetic peptide corresponding to C-terminu 15 amino acids of human AFAP1L2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of AFAP1L2 in human liver tissue lysate with AFAP1L2 polyclonal antibody (Cat # PAB16763) at (A) 1 and (B) 2 ug/mL .Western Blot (Cell lysate)
AFAP1L2 polyclonal antibody. Western Blot analysis of AFAP1L2 expression in HepG2.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of polyclonal antibody to AFAP1L2 on formalin-fixed paraffin-embedded human kidney. [antibody concentration 3 ug/ml]Immunohistochemistry
Immunohistochemistry of AFAP1L2 in human liver tissue with AFAP1L2 polyclonal antibody (Cat # PAB16763) at 2.5 ug/mL .Enzyme-linked Immunoabsorbent Assay
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Gene Info — AFAP1L2
Entrez GeneID
84632Protein Accession#
NP_001001936Gene Name
AFAP1L2
Gene Alias
FLJ14564, KIAA1914, XB130
Gene Description
actin filament associated protein 1-like 2
Gene Ontology
HyperlinkOther Designations
CTB-1144G6.4|KIAA1914 protein|OTTHUMP00000020527|OTTHUMP00000020528
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Interactome
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Disease
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Publication Reference
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High XB130 expression in renal cell carcinoma is strongly associated with poor prognosis.
Piti Ungarreevittaya, Orapin Nintra, Wichien Sirithanaphol, Jarin Chindaprasirt, Sakkarn Sangkhamanon.
Annals of Diagnostic Pathology 2023 Aug; 67:152190.
Application:IHC, Human, Renal cell carcinoma.
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Prognostic significance of XB130 expression in surgically resected pancreatic ductal adenocarcinoma.
Zhang J, Jiang X, Zhang J.
World Journal of Surgical Oncology 2014 Mar; 12(1):49.
Application:IHC, Human, Pancreatic ductal adenocarcinoma.
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XB130, a tissue-specific adaptor protein that couples the RET/PTC oncogenic kinase to PI 3-kinase pathway.
Lodyga M, De Falco V, Bai XH, Kapus A, Melillo RM, Santoro M, Liu M.
Oncogene 2009 Feb; 28(7):937.
Application:IHC, IP, WB-Tr, Human, HEK 293T cells, Human papillary thyroid cancer, TPC1 cells.
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XB130, a novel adaptor protein for signal transduction.
Xu J, Bai XH, Lodyga M, Han B, Xiao H, Keshavjee S, Hu J, Zhang H, Yang BB, Liu M.
The Journal of Biological Chemistry 2007 Jun; 282(22):16401.
Application:IF, IP, WB, Human, 3Y1, A-549, BEAS-2B cells.
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High XB130 expression in renal cell carcinoma is strongly associated with poor prognosis.
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