EFEMP1 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of EFEMP1 in HeLa cell lysate with EFEMP1 polyclonal antibody (Cat # PAB16759) at (A) 0.5 and (B) 1 ug/mL .
Immunocytochemistry
Immunocytochemistry of EFEMP1 in HeLa cells with EFEMP1 polyclonal antibody (Cat # PAB16759) at 20 ug/mL .
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of EFEMP1.
Immunogen
A synthetic peptide corresponding to C-terminus 19 amino acids of human EFEMP1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of EFEMP1 in HeLa cell lysate with EFEMP1 polyclonal antibody (Cat # PAB16759) at (A) 0.5 and (B) 1 ug/mL .Immunocytochemistry
Immunocytochemistry of EFEMP1 in HeLa cells with EFEMP1 polyclonal antibody (Cat # PAB16759) at 20 ug/mL .Enzyme-linked Immunoabsorbent Assay
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Gene Info — EFEMP1
Entrez GeneID
2202Protein Accession#
NP_004096Gene Name
EFEMP1
Gene Alias
DHRD, DRAD, FBLN3, FBNL, FLJ35535, MGC111353, MLVT, MTLV, S1-5
Gene Description
EGF-containing fibulin-like extracellular matrix protein 1
Gene Ontology
HyperlinkGene Summary
This gene spans approximately 18 kb of genomic DNA and consists of 12 exons. Alternative splice patterns in the 5' UTR result in three transcript variants encoding the same extracellular matrix protein. Mutations in this gene are associated with Doyne honeycomb retinal dystrophy. [provided by RefSeq
Other Designations
fibrillin-like|fibulin 3
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Interactome
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Disease
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Publication Reference
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EFEMP1 expression promotes in vivo tumor growth in human pancreatic adenocarcinoma.
Seeliger H, Camaj P, Ischenko I, Kleespies A, De Toni EN, Thieme SE, Blum H, Assmann G, Jauch KW, Bruns CJ.
Molecular Cancer Research 2009 Feb; 7(2):189.
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Lack of fibulin-3 causes early aging and herniation, but not macular degeneration in mice.
McLaughlin PJ, Bakall B, Choi J, Liu Z, Sasaki T, Davis EC, Marmorstein AD, Marmorstein LY.
Human Molecular Genetics 2007 Dec; 16(24):3059.
Application：WB-Ti, Mouse, Mouse lung.
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A comparative analysis of the fibulin protein family. Biochemical characterization, binding interactions, and tissue localization.
Kobayashi N, Kostka G, Garbe JH, Keene DR, Bachinger HP, Hanisch FG, Markova D, Tsuda T, Timpl R, Chu ML, Sasaki T.
The Journal of Biological Chemistry 2007 Feb; 282(16):11805.
Application：RIA, WB-Ti, Mouse, Mouse Aorta, Brain, Esophagus, Heart, Intestine, Lung, Kidney, Planceta, Skeletal muscle, Skin, Spleen, Stomach, Testis, Thymus.
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EFEMP1 expression promotes in vivo tumor growth in human pancreatic adenocarcinoma.
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