TNFAIP3 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TNFAIP3.
Immunogen
A synthetic peptide corresponding to internal region 17 amino acids of human TNFAIP3.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Tissue lysate)
Western blot analysis of TNFAIP3 in rat lung tissue lysate with TNFAIP3 polyclonal antibody (Cat # PAB16740) at (A) 1 and (B) 2 ug/mL .Immunohistochemistry
Immunohistochemistry of TNFAIP3 in human lung tissue with TNFAIP3 polyclonal antibody (Cat # PAB16740) at 5 ug/mL .Enzyme-linked Immunoabsorbent Assay
-
Gene Info — TNFAIP3
Entrez GeneID
7128Protein Accession#
Q60769Gene Name
TNFAIP3
Gene Alias
A20, MGC104522, MGC138687, MGC138688, OTUD7C, TNFA1P2
Gene Description
tumor necrosis factor, alpha-induced protein 3
Omim ID
191163Gene Ontology
HyperlinkGene Summary
This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. Knockout studies of a similar gene in mice suggested that this gene is critical for limiting inflammation by terminating TNF-induced NF-kappa B responses. [provided by RefSeq
Other Designations
OTTHUMP00000017289|tumor necrosis factor inducible protein A20
-
Interactome
-
Disease
-
Publication Reference
-
TNFAIP3/A20 functions as a novel tumor suppressor gene in several subtypes of non-Hodgkin lymphomas.
Honma K, Tsuzuki S, Nakagawa M, Tagawa H, Nakamura S, Morishima Y, Seto M.
Blood 2009 Jul; 114(12):2467.
-
TNFAIP3 (A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma.
Schmitz R, Hansmann ML, Bohle V, Martin-Subero JI, Hartmann S, Mechtersheimer G, Klapper W, Vater I, Giefing M, Gesk S, Stanelle J, Siebert R, Kuppers R.
The Journal of Experimental Medicine 2009 Apr; 206(5):981.
-
A 3-cM commonly deleted region in 6q21 in leukemias and lymphomas delineated by fluorescence in situ hybridization.
Zhang Y, Matthiesen P, Harder S, Siebert R, Castoldi G, Calasanz MJ, Wong KF, Rosenwald A, Ott G, Atkin NB, Schlegelberger B.
Genes, Chromosomes & Cancer 2000 Jan; 27(1):52.
-
TNFAIP3/A20 functions as a novel tumor suppressor gene in several subtypes of non-Hodgkin lymphomas.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com