MATN3 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of MATN3.
Immunogen
A synthetic peptide corresponding to C-terminus 13 amino acids from of human MATN3.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of MATN3 in NIH/3T3 cell lysate with MATN3 polyclonal antibody (Cat # PAB16732) at (A) 1 and (B) 2 ug/mL .Immunocytochemistry
Immunocytochemistry of MATN3 in NIH/3T3 cells with MATN3 polyclonal antibody (Cat # PAB16732) at 5 ug/mL .Enzyme-linked Immunoabsorbent Assay
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Gene Info — MATN3
Entrez GeneID
4148Protein Accession#
AAI39908Gene Name
MATN3
Gene Alias
EDM5, HOA
Gene Description
matrilin 3
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of von Willebrand factor A domain containing protein family. This family of proteins is thought to be involved in the formation of filamentous networks in the extracellular matrices of various tissues. This protein contains two von Willebrand factor A domains; it is present in the cartilage extracellular matrix and has a role in the development and homeostasis of cartilage and bone. Mutations in this gene result in multiple epiphyseal dysplasia. [provided by RefSeq
Other Designations
matrilin-3 alternative transcript
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Interactome
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Disease
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Publication Reference
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Enhancing and maintaining chondrogenesis of synovial fibroblasts by cartilage extracellular matrix protein matrilins.
Pei M, Luo J, Chen Q.
Osteoarthritis and Cartilage 2008 Feb; 16(9):1110.
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Characterization of the matrilin coiled-coil domains reveals seven novel isoforms.
Frank S, Schulthess T, Landwehr R, Lustig A, Mini T, Jeno P, Engel J, Kammerer RA.
The Journal of Biological Chemistry 2002 Mar; 277(21):19071.
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Assessment of the gene expression profile of differentiated and dedifferentiated human fetal chondrocytes by microarray analysis.
Stokes DG, Liu G, Coimbra IB, Piera-Velazquez S, Crowl RM, Jimenez SA.
Arthritis and Rheumatism 2002 Feb; 46(2):404.
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Enhancing and maintaining chondrogenesis of synovial fibroblasts by cartilage extracellular matrix protein matrilins.
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