C13orf34 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of C13orf34 in Jurkat cell lysate with C13orf34 polyclonal antibody (Cat # PAB16727) at (A) 1 and (B) 2 ug/mL .
Immunohistochemistry
Immunohistochemistry of C13orf34 in mouse brain tissue with C13orf34 polyclonal antibody (Cat # PAB16727) at 2.5 ug/mL .
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of C13orf34.
Immunogen
A synthetic peptide corresponding to N-terminus 15 amino acids from of human C13orf34.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of C13orf34 in Jurkat cell lysate with C13orf34 polyclonal antibody (Cat # PAB16727) at (A) 1 and (B) 2 ug/mL .Immunohistochemistry
Immunohistochemistry of C13orf34 in mouse brain tissue with C13orf34 polyclonal antibody (Cat # PAB16727) at 2.5 ug/mL .Enzyme-linked Immunoabsorbent Assay
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Gene Info — C13orf34
Entrez GeneID
79866Protein Accession#
Q6PGQ7Gene Name
C13orf34
Gene Alias
BORA, FLJ22624
Gene Description
chromosome 13 open reading frame 34
Omim ID
610510Gene Ontology
HyperlinkGene Summary
BORA is an activator of the protein kinase Aurora A (AURKA; MIM 603072), which is required for centrosome maturation, spindle assembly, and asymmetric protein localization during mitosis (Hutterer et al., 2006 [PubMed 16890155]).[supplied by OMIM
Other Designations
OTTHUMP00000018495|aurora borealis
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Interactome
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Publication Reference
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Roles of Aurora kinases in mitosis and tumorigenesis.
Fu J, Bian M, Jiang Q, Zhang C.
Molecular Cancer Research 2007 Jan; 5(1):1.
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Mitotic activation of the kinase Aurora-A requires its binding partner Bora.
Hutterer A, Berdnik D, Wirtz-Peitz F, Zigman M, Schleiffer A, Knoblich JA.
Developmental Cell 2006 Aug; 11(2):147.
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What's so Bor(a)ing about Aurora-A activation?
Wiese C, O'Brien LL.
Developmental Cell 2006 Aug; 11(2):133.
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Roles of Aurora kinases in mitosis and tumorigenesis.
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