RCAN2 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of RCAN2.
Immunogen
A synthetic peptide corresponding to internal region 14 amino acids of human RCAN2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of RCAN2 in NIH/3T3 cell lysate with RCAN2 polyclonal antibody (Cat # PAB16706) at (A) 1 and (B) 2 ug/mL .Immunohistochemistry
Immunohistochemical staining of mouse brain tissue with 2.5 ug/mL RCAN2 polyclonal antibody (Cat # PAB16706).Enzyme-linked Immunoabsorbent Assay
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Gene Info — RCAN2
Entrez GeneID
10231Protein Accession#
AAH62141 (Mouse)Gene Name
RCAN2
Gene Alias
CSP2, DSCR1L1, MCIP2, RCN2, ZAKI-4, ZAKI4, hRCN2
Gene Description
regulator of calcineurin 2
Omim ID
604876Gene Ontology
HyperlinkOther Designations
Calcipressin 2 (Thyroid hormone-responsive protein ZAKI-4) (Down syndrome candidate region 1-like 1) (Myocyte-enriched calcineurin interacting protein 2) (MCIP2)|Down syndrome candidate region 1-like 1|Down syndrome critical region gene 1-like 1|Down synd
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Interactome
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Disease
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Publication Reference
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Novel human ZAKI-4 isoforms: hormonal and tissue-specific regulation and function as calcineurin inhibitors.
Cao X, Kambe F, Miyazaki T, Sarkar D, Ohmori S, Seo H.
The Biochemical Journal 2002 Oct; 367(Pt 2):459.
Application:IP, Human, Skin fibroblasts.
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DSCR1, overexpressed in Down syndrome, is an inhibitor of calcineurin-mediated signaling pathways.
Fuentes JJ, Genesca L, Kingsbury TJ, Cunningham KW, Perez-Riba M, Estivill X, de la Luna S.
Human Molecular Genetics 2000 Jul; 9(11):1681.
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A protein encoded within the Down syndrome critical region is enriched in striated muscles and inhibits calcineurin signaling.
Rothermel B, Vega RB, Yang J, Wu H, Bassel-Duby R, Williams RS.
The Journal of Biological Chemistry 2000 Mar; 275(12):8719.
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Novel human ZAKI-4 isoforms: hormonal and tissue-specific regulation and function as calcineurin inhibitors.
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