TTBK1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TTBK1.
Immunogen
A synthetic peptide corresponding to C-terminus 16 amino acids of human TTBK1.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Recommend Usage
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of TTBK1 in Jurkat cell lysate with TTBK1 polyclonal antibody (Cat # PAB16697) at 1 ug/mL .Immunohistochemistry
Immunohistochemical staining of mouse brain tissue with 2.5 ug/mL TTBK1 polyclonal antibody (Cat # PAB16697).Enzyme-linked Immunoabsorbent Assay
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Gene Info — TTBK1
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Interactome
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Publication Reference
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Spatial learning impairment, enhanced CDK5/p35 activity, and downregulation of NMDA receptor expression in transgenic mice expressing tau-tubulin kinase 1.
Sato S, Xu J, Okuyama S, Martinez LB, Walsh SM, Jacobsen MT, Swan RJ, Schlautman JD, Ciborowski P, Ikezu T.
Journal of Neuroscience 2008 Dec; 28(53):14511.
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Tau-tubulin kinase 1 (TTBK1), a neuron-specific tau kinase candidate, is involved in tau phosphorylation and aggregation.
Sato S, Cerny RL, Buescher JL, Ikezu T.
Journal of Neurochemistry 2006 Sep; 98(5):1573.
Application:WB-Tr, Monkey, COS-7, HEK 293 cells.
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Spatial learning impairment, enhanced CDK5/p35 activity, and downregulation of NMDA receptor expression in transgenic mice expressing tau-tubulin kinase 1.
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