PDCD5 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of PDCD5 in EL4 cell lysate with PDCD5 polyclonal antibody (Cat # PAB16696) at 1 ug/mL .
Immunocytochemistry
Immunocytochemistry of PDCD5 in Jurkat cells with PDCD5 polyclonal antibody (Cat # PAB16696) at 2 ug/mL .
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of PDCD5.
Immunogen
A synthetic peptide corresponding to C-terminus 21 amino acids of human PDCD5.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of PDCD5 in EL4 cell lysate with PDCD5 polyclonal antibody (Cat # PAB16696) at 1 ug/mL .Immunocytochemistry
Immunocytochemistry of PDCD5 in Jurkat cells with PDCD5 polyclonal antibody (Cat # PAB16696) at 2 ug/mL .Enzyme-linked Immunoabsorbent Assay
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Gene Info — PDCD5
Entrez GeneID
9141Gene Name
PDCD5
Gene Alias
MGC9294, TFAR19
Gene Description
programmed cell death 5
Omim ID
604583Gene Ontology
HyperlinkGene Summary
This gene encodes a protein expressed in tumor cells during apoptosis independent of the apoptosis-inducing stimuli. Prior to apoptosis induction, this gene product is distributed in both the nucleus and cytoplasm. Once apoptosis is induced, the level of this protein increases and by relocation from the cytoplasm, it accumulates in the nucleus. Although its exact function is not defined, this protein is thought to play an early and universal role in apoptosis. [provided by RefSeq
Other Designations
TF1 cell apoptosis-related gene 19|TFAR19 novel apoptosis-related
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Interactome
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Disease
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Publication Reference
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Structure-function correlation of human programmed cell death 5 protein.
Yao H, Xu L, Feng Y, Liu D, Chen Y, Wang J.
Archives of Biochemistry and Biophysics 2009 Apr; 486(2):141.
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An alternative form of paraptosis-like cell death, triggered by TAJ/TROY and enhanced by PDCD5 overexpression.
Wang Y, Li X, Wang L, Ding P, Zhang Y, Han W, Ma D.
Journal of Cell Science 2004 Mar; 117(Pt 8):1525.
Application：Flow Cyt, Human, HEK 293T cells.
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Nuclear translocation of PDCD5 (TFAR19): an early signal for apoptosis?
Chen Y, Sun R, Han W, Zhang Y, Song Q, Di C, Ma D.
FEBS Letters 2001 Dec; 509(2):191.
Application：IF, WB-Ce, Human, HEC-1a, HEK 293, HeLa, K562, TF-1 cells.
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Structure-function correlation of human programmed cell death 5 protein.
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